The Vespiary

The Hive => Chemistry Discourse => Topic started by: alchemy_bee on April 25, 2002, 07:46:00 AM

Title: Grignard side products
Post by: alchemy_bee on April 25, 2002, 07:46:00 AM

After Hydrolysis of the grignard reagent eg with dilute HCl What are the side products? Im currious to understand what happends to the NMgCl complex.

(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000301255-file_efnm.gif)

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Can a bee be visa vis its entity when half a bee philosophically must ipso facto half not be?

Title: Mechanism
Post by: Rhodium on April 25, 2002, 10:26:00 AM

The =NMgCl complex reacts with HCl to give MgCl2 and the imine =NH, and the imine is then hydrolyzed by H2O/HCl to give the ketone =O and NH4Cl.

Title: grignard reactions
Post by: alchemy_bee on April 25, 2002, 05:23:00 PM

Whow thats great Rhodium, its easy to see how water is detramental to NaBH3 reductions of P2Ps.

Can you explain the attraction/reaction of the nitrogen in the methyl cyanide to the grignard set (MgCl)?


To any bees interested in grignard reactions

http://www.chem.ucalgary.ca/courses/351/Carey/Ch14/ch14-3-1.html (http://www.chem.ucalgary.ca/courses/351/Carey/Ch14/ch14-3-1.html)

is a good read.

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Can a bee be visa vis its entity when half a bee philosophically must ipso facto half not be?

Title: RMgX + RCN
Post by: Rhodium on April 26, 2002, 04:12:00 AM

One of the resonance forms of a nitrile is R-C⁺=N^- and the grignard reagent is equivalent to a R^- anion, therefore it adds to the nitrile carbon.