The Vespiary

The Hive => Tryptamine Chemistry => Topic started by: n00dle on June 14, 2004, 08:19:00 AM

Title: IAA/I3A biosynth ref...?
Post by: n00dle on June 14, 2004, 08:19:00 AM

http://www.ejbiochem.org/cgi/reprint/270/10/2322 (http://www.ejbiochem.org/cgi/reprint/270/10/2322)


in that document..

"...according toHansch et al.
[Hansch, C., Leo, A., Unger, S.H.,Kim,K.H., Nikaitani,D
& Lien, E.J. (1973) J. Med. Chem. 16, 1207–1216] and
comparison with indole-3-pyruvic acid conversion by pyruvate
decarboxylases from Saccharomyces cerevisiae..."

Was thinking someone could use both these references. I dont understand it fully but according to the diagram, IPDC works tryptophan to IAA. if someone could figure out how to inhibit the last step, one could make a turkey/salmon fermentation to end up with indole-acetaldehyde. The actual page even talks about this formation occuring in saccharomyces spp. so one could assume maybe conditions could be tweaked to allow bakers yeast to perform this synthesis rather than some wierd cucumber extract.
So yeah, apologies if this is irrelevant to anything just thought someone could use it for food for thought, else delete post, no biggie