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NBS bromination of 2,4-dimethoxyphenylethylamine

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Bandil:
Any idea what 4-iodo-2,4-dimethoxphenylethylamine would be like?

Non existant, as the 4 position only holds one substitutent hehe...

However 2,4-dimethoxy-5-iodo-PEA, might be another story (although very likely to be inactive...)

Regards
Bandil
*kiss kiss*  8)

Captain_America:
2,4-dimethoxy-5-halo-amphetamines are active, META-DOB have according to Pihkal at a dosage of about 100 milligrams produced effects that were similar to those produced by MDA. Seem to bee some toxic sines involved. Vaaugh, are you going to taste this META-2CB? I don't think it will bee active. Look at TMPEA, 2C analog of TMA-2, it is inactive while TMA-2 is turbulantly active comound. So there is no reason to believe that META-2CB will bee active, it will bee even less active than TMPEA as META-DOB is less active than TMA-2. It is the same pattern/relationship. But in combination it might boost the effects of some other compound.

Vaaguh:
Meta-2c-b won't be tasted by me for now. NBS is just a really attractive bromination agent compared to elemental bromine in these cases, especially since no additional catalyst is required and the reaction time is pretty short.

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