Author Topic: hydroxalamine in nabh3cn?  (Read 2615 times)

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ZZACk

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hydroxalamine in nabh3cn?
« on: November 27, 2001, 04:39:00 PM »
if one were to  use a dry meoh/ ketone solution and use hydroxylamine instead os annac or methylamine in a slightly acidic solution.before adding nabh3cn.
would one make mdoh or would they have to form the oxime then rereduce it?
hypothetically speaking of course.
Z

Go Ugly Early

Rhodium

  • Guest
Re: hydroxalamine in nabh3cn?
« Reply #1 on: November 27, 2001, 06:05:00 PM »
That would produce MDOH, see

http://www.erowid.org/library/books_online/pihkal/pihkal114.shtml



If MDOH is heated too much (as in distillation for example), it disproportionates into MDA and MDP2P oxime.

ZZACk

  • Guest
Re: hydroxalamine in nabh3cn?
« Reply #2 on: November 28, 2001, 10:57:00 AM »
thanks rhod,
would one go about extracting the unreduced ketone, and removing the mdoh in dcm and then gassing or would another solvednt bee better? also how would one remove the meoh without convertingf the mhoh to oxime and mda i would guess with a vaccum distillation.
Z

Go Ugly Early

Rhodium

  • Guest
Re: hydroxalamine in nabh3cn?
« Reply #3 on: November 28, 2001, 12:30:00 PM »
Follow the exact procedure in Pihkal and you'll be fine. There is very little unreduced ketone in there, mostly the ketone reduced to the alcohol.