I was checking out the method on Rhodium's page listed here:
https://www.thevespiary.org/rhodium/Rhodium/chemistry/mdp2p.dibromide.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/mdp2p.dibromide.html)
I had a question about it.
The conversion of the Isosafroleepoxide into the ketone starts when the epoxide is heated to 220°C in a flask equipped with a air-cooled condenser. The temperature jumps up quickly to 280°C. When the exothermic rxn has finished, the mix is refluxed for a short period of time. The first destillation under normal pressure yields a colorless, almost non-smelling oil, which comes over between 280-290°C. Under 10mm pressure it boils between 149-151°C. Yield 80%
Does this reaction result in tar being formed all over your condensor, or does the ketone not degrade that fast? Also, colorless and odorless does not describe any MDP2P I've seen. Everything I've known to be MDP2P was a pale yellow that changed in intensity depending on how you refracted light through it. It also always had that burnt potpouri smell to it. Can ketone truly be colorless and odorless?
All paths are the same: they lead nowhere
ETHER
General. Introduced in the early 18th century as a medicine and solvent, ether is not widely used recreationally until the 19th century. By the 1840's, when its anesthetic properties are discovered, ether frolics produced either by inhalation or by drinking a drops of ether in water are already common among the upper classes (mostly youths) of Europe and America.
Ireland. Ether is introduced into N. Ireland as a preventive and folk remedy (1840); recreational drinking spreads in the Ulster counties of Londonderry and Tyrone, possibly begun by the example of a physician in Draperstown. Poverty, temperance crusades, and high alcohol taxes (1855) encourage its use as a cheap, readily available alcohol substitute, especially by lower class Catholics. Priests begin attempts to suppress ether drinking by cursing it as a sin (1869).
Extract from http://mir.drugtext.org/ibogaine/drughist.html (http://mir.drugtext.org/ibogaine/drughist.html)
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