The Vespiary

The Hive => Novel Discourse => Topic started by: El_Zorro on January 03, 2003, 09:53:00 AM

Title: solvent inert to CaC2?
Post by: El_Zorro on January 03, 2003, 09:53:00 AM: What solvents are inert towards CaC₂? More specifically, one that acetamide would be fairly soluble in.
Title: What?
Post by: pHarmacist on January 03, 2003, 09:55:00 AM: What does this has to do with: Novel synthetic routes to psychoactive materials
Title: Well, I didn't really mention it in the ...
Post by: El_Zorro on January 03, 2003, 10:14:00 AM: Well, I didn't really mention it in the question but I was asking this so that I could start forming a procedure for dehydrating acetamide to acetonitrile. So if anybody has thoughts on that too, I'd like to hear them.
Title: Solvents compatible with calcium carbide
Post by: Rhodium on January 03, 2003, 10:45:00 AM: You want a solvent not containing any acidic hydrogens or other functional groups sensitive to bases. Such solvents include hydrocarbons (like hexane/toluene) and ethers (THF/Et₂O).

Chlorinated hydrocarbons (DCM, chloroform) might react, so don't use them just to be safe. Esters, alcohols and ketones and any solvents not properly dried are directly unsuitable.
Title: Would CaC2 dissolve in benzaldehyde, forming...
Post by: Tengo on January 03, 2003, 06:07:00 PM: Would CaC2 dissolve in benzaldehyde, forming (after acidification) 1,4-diphenyl-1,4-dihydroxy-2-butyne?
CaC2 + 2Ph-CHO -> Ph-C(OH)-C---C-C(OH)-Ph
Title: According to what mechanism?
Post by: Rhodium on January 03, 2003, 06:43:00 PM: According to what mechanism?
Title: Just a thought... C 2 2- being such a strong...
Post by: Tengo on January 03, 2003, 07:56:00 PM: Just a thought... C₂2- being such a strong base, that it would add to the carbonyl and making a hydroxy... S_N2 basically... Well... a nucleophile attack anyway...
If CaC2 won't dissolve in benzaldehyde, then this wouldn't work. But perhaps with another solvent...?
Title: Anybody...any knowledge about this...?
Post by: Tengo on January 12, 2003, 05:24:00 AM: Anybody...any knowledge about this...?
Title: Maybe you could heat acetamide and CaC2 ...
Post by: PolytheneSam on January 12, 2003, 04:44:00 PM: Maybe you could heat acetamide and CaC2 together without a solvent. Try a small amount in a test tube. You could connect a one hole rubber stopper and 90 degree piece of glass tubing to the test tube and then connect a condenser to it and see if you can distill off any CH3CN.