Patent US5656648
, as well as
Chem. Pharm. Bull. 39(9), 2400-2407 (1991) (quoted in that patent) describes the alkylation (1. BuLi 2. E
+, or AlCl
3 + ClCH
2COCl) of various 1-substituted (Halo, Alkyl, Trifluoromethyl) 3,5-Dimethoxybenzenes, which make
excellent precursors for pseudo-2C-X compounds (4-substituted 2,6-dimethoxyphenethylamines).
These compounds should be about equipotent to the 2C-X counterparts, as well as showing a similar spectrum of effects. That should also be legal in many parts of the world. Further reading on this topic:
Post 122771
(dormouse: "Synthetic challenge: Pseudo 2C-B -Rhodium", Serious Chemistry)Could anyone fetch that article, please?