That too. Any lewis acid does the job.
Rhodium, could you use aluminum chloride (AlCl3)? And if so, would the hydrated form be suitable? I'm referring to the hydrate produced upon addition of muriatic to Al foil.
PrimoPyro
https://www.thevespiary.org/rhodium/Rhodium/chemistry/safrolepoxide.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/safrolepoxide.html)
) . It worked for anethole as specified.Post 218193 (missing)
(Ritter: "LiI catalyzed pinacol rearrangement possible?", Chemistry Discourse)http://astro.ocis.temple.edu/~dalton/drdcv.htm (http://astro.ocis.temple.edu/~dalton/drdcv.htm)
If you make the 2,3-epoxide, it can be rearranged to MDP2P using LiI, LiBr and MgBr2 (among other reagents), but if it is subjected to the regular isosafrole treatment, there is a big risk that undesired aldehydes are formed instead.
Do you mean by 'regular treatment' the rearrangement of the (2,3) epoxide using H2SO4? Or the whole peracid / rearrangement process applied to safrol?
Post 236297 (https://www.thevespiary.org/talk/index.php?topic=12224.msg23629700#msg23629700)
(Chromic: "anethole -> epoxide", Novel Discourse). I also wonder why no one has investigated this route... and I don't get why no one has investigated the route to the diol by slowly dripping in a concentrated solution of KMnO4.Post 228375 (https://www.thevespiary.org/talk/index.php?topic=11411.msg22837500#msg22837500)
(Ritter: "Re: Ketones from Propenylbenzenes via the di-bromides", Novel Discourse)Post 227831 (https://www.thevespiary.org/talk/index.php?topic=11411.msg22783100#msg22783100)
(uemura: "Ketones from Propenylbenzenes via the di-bromides", Novel Discourse)Post 241293 (https://www.thevespiary.org/talk/index.php?topic=11347.msg24129300#msg24129300)
(uemura: "Properties of some epoxides", Novel Discourse)Post 243262 (https://www.thevespiary.org/talk/index.php?topic=8989.msg24326200#msg24326200)
(uemura: "Epoxide Rearrangement Example", Methods Discourse)Post 280991 (https://www.thevespiary.org/talk/index.php?topic=8999.msg28099100#msg28099100)
(LaBTop: "Isosafrole Epoxide Thermal Rearrangement Review", Methods Discourse)Chem. Ber. 37, 1542-1560 (1904) (https://www.thevespiary.org/rhodium/Rhodium/pdf/hoering.anethol.pdf)
(https://www.thevespiary.org/rhodium/Rhodium/pdf/hoering.anethol.pdf)Chem. Ber. 38, 2296-2299 (1905) (https://www.thevespiary.org/rhodium/Rhodium/pdf/hoering.epoxide2ketone.pdf)
(https://www.thevespiary.org/rhodium/Rhodium/pdf/hoering.epoxide2ketone.pdf)Chem. Ber. 38, 3458-3463 (1905) (https://www.thevespiary.org/rhodium/Rhodium/pdf/hoering.dibromide-3.pdf)
(https://www.thevespiary.org/rhodium/Rhodium/pdf/hoering.dibromide-3.pdf)Chem. Ber. 38, 3464-3476 (1905) (https://www.thevespiary.org/rhodium/Rhodium/pdf/hoering.dibromide-4.pdf)
(https://www.thevespiary.org/rhodium/Rhodium/pdf/hoering.dibromide-4.pdf)Chem. Ber. 38, 3477-3488 (1905) (https://www.thevespiary.org/rhodium/Rhodium/pdf/hoering.dibromide-5.pdf)
(https://www.thevespiary.org/rhodium/Rhodium/pdf/hoering.dibromide-5.pdf)