This came up in the general forum 3 monthes ago
posted 10-12-1999 09:03 AM
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This will seem pathetic, but is the d- or l- isomer the desired one, and how exactly is pseudoephedrine different from ephedrine (just stereochemistry or r they consitutionally different)
Also are any of these compounds at all stimulating on there own, or dangerous? (i know of an OTC medicine which is DXM and pseudo, any problems there?)
Acme
Member posted 10-12-1999 01:58 PM
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Hoping you can deciper this shorthand
They both have the formula
C6H5CH[CH(NHCH3)CH3]OH
they differ in stereochemistry
eph (-) 1R,2S
eph (+) 1S,2R
psu (-) 1R,2R
psu (+) 1S,2S
Not sure which is called d- or l- . It would be a wild guess to say (+) is d im just not sure.
Hopefully some wiser bee can clue us in on which is d or l and which one would be best (for your cold, of course)
CHEM GUY
Member posted 10-12-1999 02:00 PM
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Slappy, where did you get that info? I'm not questioning you but I just want the reference-
CHEM GUY
Member posted 10-12-1999 09:15 PM
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From Fornsic science international, 48 (1990), 123-34
"...(-) ephedrine or (+) pseudoephedrine yeilds (+) methamphetamine."
From the journal of Forensic science, page 956
"...(-) ephedrine and (+) pseudoephedrine yeild d-methamphetamine"
Therefore (+) methamphetamine is d-methamphetamine.