Since this is my first post I would like to thank Dr. Shulgun, Strike, Rhodium, Osmium, and to many other bees to list, especially all the moderators. Your knowledge makes for beautiful dreams.
So I see these bears walking through the woods with a flask and a copy of pihkal. Turns out these were honey bears and they wanted to ask some bees a few questions about some rare honey(at least in this forest). Since bears aint so good with computers I am going to help them out.
Refering to the mescaline synth. in pihkal or more explicitly to the reduction:
1. Why do you add the rochele salt?
2. Could this be scaled up using LAH and THF under helium? Say 10 times the size in pihkal. As writen it seams like a lot of work for very little product.
3. Whats the selflife of the nitrostyrene?
4. Any obvious reasons this reduction can't be done with the Zn/HCl method. Seams like if it works fo 2C-H, it should work for mescaline.
Thanks