Author Topic: MDMA methylene homolog being sold as party drug in the Phillipines  (Read 4082 times)

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Offline Beard

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From: xttp://newsinfo.inquirer.net/788527/nbi-lab-chemical-unfit-for-humans-sold-by-pushers

Quote
NBI: Lab chemical unfit for humans sold by pushers

Philippine Daily Inquirer
11:49 PM May 31st, 2016

A CHEAPER and more dangerous version of ecstasy is being sold in the local market although its trade and use have yet to be considered illegal.

National Bureau of Investigation forensics division chief of staff Romel Papa said on Tuesday that MDMA methylene homolog had the same effect as ecstasy.

However, the substance—a laboratory drug used in forensic research—has yet to be included in the list of prohibited drugs under the law.

“What is MDMA methylene homolog? It’s a chemical being utilized for forensic and laboratory research. It’s a laboratory chemical and unfit for human consumption or veterinary use, making it more dangerous. This substance was never studied on human subjects,” Papa told reporters.

Its trade was discovered after the NBI anti-illegal drugs division led by Joel Tovera arrested on Saturday Joshua Habalo who yielded MDMA methylene homolog which came in pink tablets. “I was informed initially that those items were similar or connected with the drugs taken by the victims in the Pasay concert,” Tovera said.

Not a great article... I'm pretty sure this stuff is the result of reductive amination of helional with methylamine. It first started showing up a few years ago.

More info:
xttp://www.swgdrug.org/Monographs/3,4-MDMA%20methylene%20homolog.pdf
xttps://www.caymanchem.com/app/template/Product.vm/catalog/10979
xttp://www.bluelight.org/vb/threads/674279-MDMA-Methylene-homolog
« Last Edit: June 02, 2016, 09:49:16 PM by Beard »

Offline Tsathoggua

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Re: MDMA methylene homolog being sold as party drug in the Phillipines
« Reply #1 on: June 03, 2016, 03:17:13 AM »
Might they mean the indane?

Crap article from the shite you posted (not a criticism of you, but of the journalism btw)

So...its never been studied and as such 'we' don't know a damn thing about it, and its more dangerous than MDMA, although we don't know how it affects people?
Come on...tsath knows that journos are stupid bastards, but thats a bit much. you don't even need to know weather its a drug being spoken of, or a bag of iron filings. If you have no idea weather  or not its safe
or dangerous, because nobody has ever even researched to find out, then how can one claim the thing spoken of, ANY thing, regardless of what it is, how can someone be such an irredeemable, hopeless fucking cretin as to claim its more dangerous, in the same damn breath as saying that they haven't a bloody clue how safe it is.

Christ. If Tsath' were to own a media outlet and publish a paper, and one of his journalists wrote and printed an article like that, they would get ONE warning. Violate it, fuck up like that again after being given the gigantic luxury of a chance at making good, and they wouldn't even get to pack their stuff, clear their desk and leave. They'd be going out of the top floor window, and three or four other floors as well, at the same time.
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Offline dopamine

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Re: MDMA methylene homolog being sold as party drug in the Phillipines
« Reply #2 on: June 07, 2016, 05:09:18 PM »
Might they mean the indane?

Crap article from the shite you posted (not a criticism of you, but of the journalism btw)

So...its never been studied and as such 'we' don't know a damn thing about it, and its more dangerous than MDMA, although we don't know how it affects people?
Come on...tsath knows that journos are stupid bastards, but thats a bit much. you don't even need to know weather its a drug being spoken of, or a bag of iron filings. If you have no idea weather  or not its safe
or dangerous, because nobody has ever even researched to find out, then how can one claim the thing spoken of, ANY thing, regardless of what it is, how can someone be such an irredeemable, hopeless fucking cretin as to claim its more dangerous, in the same damn breath as saying that they haven't a bloody clue how safe it is.

Christ. If Tsath' were to own a media outlet and publish a paper, and one of his journalists wrote and printed an article like that, they would get ONE warning. Violate it, fuck up like that again after being given the gigantic luxury of a chance at making good, and they wouldn't even get to pack their stuff, clear their desk and leave. They'd be going out of the top floor window, and three or four other floors as well, at the same time.


Was about to say pretty much the same thing, but I doubt I could have worded it so humorously.

Offline Tsathoggua

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Re: MDMA methylene homolog being sold as party drug in the Phillipines
« Reply #3 on: June 08, 2016, 02:13:38 PM »
Well why thankyou, DA.

Its both appalling and saddening to bear witness to the sheer unmitigated, abject stupidity of many, or even most journos
If toady had become an editor instead of a clandestine chemist he has a strong hunch indeed that he'd have had a very high employee turnover rate, because he has a very low threshold for tolerating such putrescent, stercoraceous, foetid swill as they seem to vomit forth on a daily and indeed per article basis. In fact he'd probably have to manage the franchise from a distance and have a sortof 'on-scene' editor because hearing the usual slobbering, cryptorchid inbreeds speak  their incessant torrent of oral steatorrhea, Tsath would rapidly end up with a  Pt group metal chain of some sort, strung with legion thinner chains dangling from the horizontal axis from which to hang the dried, preserved ears and torn-out preserved tongues of
such wrongdoers as tried for a second warning. And chances are there would be a VERY high 'suicide rate'. Kind of like how some chinese facilities string 'suicide nets' below the windows to prevent employees that cannot take the shitty conditions jumping to end up as a squishy paste upon the pavement. Pavement sauce if you will:P
Only toady, would hang razor tape and barbed wire. Connecting each strand individually to a power source so as not to short it until such a prize gobshite as goes for that not-happening second warning jumps. Not enough juice to damage the circuit, most importantly. And not to kill. Just repeated shocks as one would get from a powerful cattle fence, to ensure the moron 'jumper' wriggles and writhes around in the razor/barbed wire.

When they aren't masturbating over the fly-blown roadkill which
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Offline Beard

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Re: MDMA methylene homolog being sold as party drug in the Phillipines
« Reply #4 on: June 22, 2016, 09:35:03 PM »
Might they mean the indane?

No.
Where MDMA has -NH-CH3, this has -CH2-NH-CH3.
Where helional has CH=O, this has CH2-NH-CH3.
here's a 2D drawing http://www.lipomed.com/images/mediadir/images/HLM-1404-HC.jpg

Apparently also called "Heliomethylamine".

It started showing up in BC, Canada in late 2012. https://www.ecstasydata.org/results.php?start=0&search_field=all&s=mdma+methylene
« Last Edit: June 22, 2016, 09:42:49 PM by Beard »

Offline Zippy

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Re: MDMA methylene homolog being sold as party drug in the Phillipines
« Reply #5 on: June 23, 2016, 12:07:07 AM »
I wonder if it could be found as a side product in the synthesis of MDMA via oxidative decarboxyation of Helionoic acid to MDP2P and subsequent reductive amination to MDMA. 

http://www.scielo.org.bo/img/revistas/rbq/v32n3/a01_figura13.gif

Basically unreacted helional gets carried through and reductively aminated aong with the MDP2P.

Or are people just reductively aminating helional to get the product in question which makes one wonder if this material gets people high or not.


Offline Tsathoggua

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Re: MDMA methylene homolog being sold as party drug in the Phillipines
« Reply #6 on: June 23, 2016, 06:11:16 AM »
So the beta-methyl phenyl-(sec)butyl-N-methylamine, the amine located on the sec-butyl's ?-carbon.

This is isomeric with MBDB, the difference being the sec-butyl group, the second carbon where the sidechain branches, is in the guise of an ethyl grop in MBDB, here, its relocated to being
part of the linear section of the sidechain. IMO what will make any dramatic difference if there are any is the increase in sidechain length, which in MBDB, has the amine two carbons away from the phenyl ring, in this critter, its three. Similarly theres some steric bulk due to the branching. Less in the case of this thing, a carbon more, and closer to the N-methyl amine in MBDB, which is certainly going to influence binding. On the one hand theres going to bee, assuming the sec-butyl thingy can fit properly  within the typical binding pocket at SERT, NET, DAT and whathaveye, there might well be more space if the binding pocket is small, resulting in easier binding, although Tsath' isn't well up to date on how MDxx bind with monoamine transporters on a functional group-aminoacid-of-transporters goes. Toady is conjecturing here totally, but its not impossible that lengthening the sidechain like is done in this compared with MBDB, he's thinking MAYBEE the result of fthat would be to simulate an amphetamine more closely than a phenethylamine, which if the increase in steric bulk where the sidechain branches doesn't stick out so much as in MBDB.


Considering the result of lengthening the alpha substituent from methyl to ethyl in amphetamine, to give phenisobutylamine results in a pretty dramatic loss in potency in terms of dopaminergic effects contrasted with amphetamine itself, toady thinks that the decrease in this case relative to MBDB can only be a good thing. The million-dollar question is, whats the
change from isobutyl to sec-butyl going to do.

Anyone good at receptor docking studies? if so, then it'd be fruitful IMO to compare binding at NET, SERT and DAT between MDMA, MBDB, the alpha-ethyl homolog of MDMA, and overlaiy each with this sec-butyl critter.
Nomen mihi Legio est, quia multi sumus

I'm hyperbolic, hypergolic, viral, chiral. So motherfucking twisted my laevo is on the right side.