Hi there bees! This is my first post.
After reading its PiHKaL entry, 2C-N triggered my attention. Dr. Shulgin describes similarities to MDMA but "it somehow comes up just a little short of expectations". Still he describes the material, despite having a greater body-load, as still being "okay".
There is nothing much to be found on the search engine either, except for what is mentioned in PiHKaL, and a recent post by Vitus Verdegast in General Discourse.
Inspired by Yellium's post
Post 439969
(yellium: ">I really can't figure out why this ...", Methods Discourse) I wanted to see if 2C-N also has that hidden potential that DON had, considering it's shadyness in the presence of the other more powerful 2C-X's.
And guess what: it sure holds potential!
2,5-dimethoxynitrostyrene was prepared from the corresponding aldehyde, nitromethane and EDDA catalyst according to:
https://www.thevespiary.org/rhodium/Rhodium/chemistry/edda.html
10 gr Nitrostyrene, recrystallised from EtOAc/EtOH as orange needles, was submitted to the Zn/HCl reduction as described by Sunlight:
Post 406397
(Sunlight: "Test done", Novel Discourse)I had a bad yield here, the cause of work up trouble, and this being the first time that I performed this reduction (as I always tend to fuck up the first time). I added the first portion of Zn over 2 hours instead of one, and after basifying and extracting with toluene I got a yelloworange organic phase.
I washed this repeatedly with water, performed an A/B with dil. sulfuric acid, basified this again and extracted with toluene. The yellow toluene layer was washed 2x with water, separated, dried over KOH, and gassed with dry HCl.
A dark coloured mess fell out of solution, which, after cleaning with ether and repeatedly with acetone, gave 1.2gr of an offwhite powder, 2,5-dimethoxyphenethylamine hydrochloride (2C-H).
2C-N600mg of 2C-H.HCl were dissolved in 7 mL GAA, followed by dropwise addition of 2 mL 60% HNO
3. Cooling wasn't necessary for this small scale, as the mixture barely increased in temperature. Towards the end of the addition yellow solids separated, stirring was continued for 5 min after addition, 5 mL of dry ether was added and the mixture was filtered. The yellow solids were washed twice with dry ether and air dried, gave 500 mgs (63%) of a beautiful yellow powder.
The nitrate salt was used for all human titrations, as was done in PiHKaL
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SWIMs results are similar but not quite the same of what it written by dr. Shulgin. He ingested the compound at 70mg, 100 mg and 120mg doses. There is a very rapid onset, effects are felt withing 30 min, like warm-and-cold sensations, pleasant body tingling and (armpit) sweating. SWIM was always giggly, good humoured and his mood was quite lifted. The body load is much bigger than the other 2C-Xs but not at all unpleasant or alarming. These are the MDMA similarities the doctor mentions. No increase in heartrate, no effects on breathing (except on 100mg my nose was suddenly cleared up), nothing.
What is different is that dr. Shulgin doesn't get any visual effects from it. For me, the compound has marked visual effects even at 70mg, and definately at 120mg, the colours and patterns reminded me of 2C-B.
Strange thing is that, at 70 & 100mg, the body load and visual effects were much more present than any psychological effects. No usual 'train of thoughts' running though my head, on contrary my thinking was suprisingly normal. Indeed a body +++ and mind ++.
But at 120mg SWIM did had profound effect on the mind which resulted in a marvelous +++ experience. The body load is always a bit heavier though.
The effects start to peak from 1 --> 2 hours, and start to wear off to be largely gone in 3 to 4 hours, depending on dose.