New, stable reducer for amination and .......

[java]

This may be of interest to some bee's, looking for a better reducing agent  for those reductive aminations and reductive methylation of amines......

Bulletin of the Chemical Society of Japan
Vol. 76  (2003) , No. 1  pp.143-151
Dichlorobis(1,4-diazabicyclo[2.2.2]octane)(tetrahydroborato)zirconium(IV), [Zr(BH4)2Cl2(dabco)2](ZrBDC), as a New, Stable, and Versatile Bench Top Reducing Agent: Reduction of Imines and Enamines, Reductive Amination of Aldehydes and Ketones and Reductive Methylation of Amines

here you can get the PDF file..........java

http://www.chemistry.or.jp/journals/bcsj/index-e.html

[java]

Just in case this was missed I brought it up for everyone's attention.It is worth a second look......java

Abstract:

The reducing agent is easily prepared in an almost quantitative yield from commercially available starting materials.
This compound is stable under mild aqueous acidic conditions (pH 4–6) and survives in H2O for several days without losing its reducing abilities. ZrBDC has been successfully used for the reduction of imines and enamines, reductive amination of aldehydes and ketones, and reductive methylation of amines.

Note:

All of the journals are available free there at J-journals in pdf form....

[Rhodium]

Zr(BH₄)₂Cl₂(dabco)₂ (ZrBDC), as a New, Stable, and Versatile Bench Top Reducing Agent:
Reduction of Imines and Enamines, Reductive Amination of Aldehydes and Ketones and Reductive Methylation of Amines
Bulletin of the Chemical Society of Japan 76(1), 143-151 (2003)
DOI:

10.1246/bcsj.76.143

(free access)

Abstract

The reducing agent is easily prepared in an almost quantitative yield from commercially available starting materials. This compound is stable under mild aqueous acidic conditions (pH 4–6) and survives in H₂O for several days without losing its reducing abilities. ZrBDC has been successfully used for the reduction of imines and enamines, reductive amination of aldehydes and ketones, and reductive methylation of amines.


See what a difference some basic editing along with the inclusion of a DOI number can do (the DOI links directly to the article). I bet that more than twice as many people got the message by reading this post compared to the two above combined, and that ten times as many actually will read the article, now that there is a link to it, rather than having people browse through the whole J-stage site to find it.