The Vespiary

The Hive => Methods Discourse => Topic started by: Bubbleplate on September 10, 2004, 01:00:00 PM

Title: Chemical Abstracts Papers Needed
Post by: Bubbleplate on September 10, 2004, 01:00:00 PM

Can anyone post a copy of the following Chemical Abstract papers:
CA 75, 77110 - 1971
CA 54, 14288 - 1960

Thank you in advance!

Title: CA 75, 77110 (1971) = CCCC 27, 1590 (1962)
Post by: Rhodium on September 10, 2004, 05:20:00 PM

One of them is excerpted in

https://www.thevespiary.org/rhodium/Rhodium/chemistry/psychedelicchemistry/chapter7.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/psychedelicchemistry/chapter7.html)

LSD From Lysergic Acid - Method 5
CCCC 27, 1590 (1962) (Cerny and Semonsky)
cf. CA 75, 77110 (1971)

To a suspension of 13.4 g dry (I) in 800 ml dry dimethylformamide (DMF) in a 2 L vacuum flask at 20ø, add a solution of 8.9 g N,N'-carbonyldiimidazole in 250 ml DMF and stir at 20ø in dark for one-half hour. Add a solution of 4 g DEA in 50 ml DMF and let stand two hours at 20ø; then twenty hours at 5ø. Evaporate in vacuum to get LSD. Can purify as above or dissolve residue in 2 1/2 L 2% tartaric acid; extract with ether and discard ether. Filter, basify with NH4OH and extract with a 9:1 solution of ether:ethanol. Dry and evaporate in vacuum to get LSD in 81% yield.

When Googling for the authors above, I found my own site:

https://www.thevespiary.org/rhodium/Rhodium/chemistry/14c-lsd.html#refs (https://www.thevespiary.org/rhodium/Rhodium/chemistry/14c-lsd.html#refs)

with ref #3 being Cerny, A. and Semonsky, M. Coll. Czech. Chem. Commun. 27, 1585 (1962)

Title: Thanks Rhodium
Post by: Bubbleplate on September 11, 2004, 04:17:00 AM

But...believe it or not, I was looking for the original Cerny and Semonsky paper because I suspect that there are errors in the formulas in the Michael Valentine Smith book's formulas!
That is, I question the molar amount of Diethylamine that is listed in Method 5. In Formula 5 it states to use " 13.4 g dry Lysergic Acid and 4 gm Diethylamine", which equates to about 5.7 ml DIE; However, in

Patent US6476199 (http://l2.espacenet.com/dips/viewer?PN=US6476199&CY=gb&LG=en&DB=EPD)

, which also uses the N,N- Carbonyl Diimidazole method, they start with 4.0 gm Lysergic Acid and use 15.2 ml Diethylamine, which is .15 mole or 10x the molar amount of Lysergic Acid. Which formula is correct??

Title: The Requested Chemical Abstracts
Post by: lugh on September 15, 2004, 02:49:00 AM

The requested available abstracts ;) Unfortunately, CA 68 36323W (1968) from

Post 531203 (https://www.thevespiary.org/talk/index.php?topic=11962.msg53120300#msg53120300)

(Bubbleplate: "Wanted : LSD References", Novel Discourse) is an inaccurate citation, no such article was found in the first half of Chemical Abstracts of 1968 ::)

CA 75, 77110 - 1971

(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_imgs/djvu.gif)

CA 54, 14288 - 1960

(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_imgs/djvu.gif)

Title: Is It Possible to Post The Links without .DJVU?
Post by: Bubbleplate on September 16, 2004, 04:51:00 AM

I have NEVER been able to open or look at any "Dejavu" files - all I get is endless downloads of pages and dead-end file associations.
Is it me or????

Title: Deja Vu Problems
Post by: lugh on September 16, 2004, 12:20:00 PM

Is it me or????

It's probably your semi-functional and outdated browser; the link works fine with up to date browsers ;) As far as Deja Vu, see

Post 218955 (https://www.thevespiary.org/talk/index.php?topic=12952.msg21895500#msg21895500)

(Antoncho: "All DejaVu programs may now bee downloaded", Tryptamine Chemistry) &

Post 494604 (missing)

(Lilienthal: "DjVu Files (better than PDF)", General Discourse); additionally Irfan View now supports Deja Vu,

http://www.irfanview.com/ (http://www.irfanview.com/)

which means there's a way to convert a compressed Deja Vu file into a much bigger Imaging file, for OCR purposes 8)

Title: Thanks Lugh! I'm A Lizard Techie Now
Post by: Bubbleplate on September 16, 2004, 01:42:00 PM

The Deja Vu files load faster, easier than PDFs! Good stuff.