Since the mighty Antoncho pointed our collective attention toward the fact benzene and acetone can bee merged to form P2P, using a characteristic single-electron oxidation of manganese (III) acetate, this virtual place has been all abuzz with the possibilities. In Post 205055 (https://www.thevespiary.org/talk/index.php?topic=11741.msg20505500#msg20505500)
(Antoncho: "P2Ps from benzene, acetone and Mn(AcO)3", Novel Discourse) you may see this develop, and in a couple documents on Rhodium's web site. This is meant to continue that thread, now grown large as befits its importance.
Very recently I learned (Post 278841 (https://www.thevespiary.org/talk/index.php?topic=11741.msg27884100#msg27884100)
(halfapint: "Acetate of Manganese", Novel Discourse)) that manganous acetate is obtainable by reducing a potassium permanganate solution in acetic acid with hydrogen peroxide, which makes it E-Z.
For us, this could bee a big one. The reaction sequence forseeable, is that this manganous acetate in acetic acid can be heated with benzene and acetone, and by periodic introduction of powdered potassium permanganate generate and regenerate manganic acetate, with progressive formation of phenyl-2-propanone.
A factor which accentuates its importance, is that p-dimethoxy benzene should undergo the same reaction, providing the basis for some extremely powerful amphetamine psychedelics, after 4-halogenation of the resultant 2,5-dimethoxy amphetamine. The substrates benzene and hydroquinone can never get sucessfully interdicted, and potassium permanganate isn't rare. Acetic acid, hydrogen peroxide and acetone aren't specialty chemicals either.
A question I have: in the manganic acetate catalyzed fusion of benzene or dimethoxybenzene with acetone in acetic acid, what is the optimal portion of water in the reaction mix? Could near anhydrous conditions prove beneficial, or can aqueous conditions provide satisfactory results?
a half a pints a half a pound a half a world a half a round
Sidearm n. Flask neck tube.