http://www.orgsyn.org/orgsyn/orgsyn/prepContent.asp?prep=cv2p0376 (http://www.orgsyn.org/orgsyn/orgsyn/prepContent.asp?prep=cv2p0376)
A solution of 600 g. of anhydrous calcium chloride in 1.8 l. of water warmed to 40° is added slowly with rapid mixing to the hot sodium malonate solution. A cheese-like precipitate of calcium malonate is formed immediately and becomes coarsely crystalline on standing for twenty-four hours. After the supernatant solution is decanted, the calcium malonate is washed by decantation four or five times with 500-cc. portions of cold water. It is then transferred to a filter, sucked as dry as possible, and dried in the air, or at 45–50°, to constant weight. The yield is 800–900 g.
The dry calcium malonate is placed in a 3-l. round-bottomed flask with sufficient (750–1000 cc.) alcohol-free ether (Note 3) to make a paste which can be stirred. The flask is surrounded by an ice bath, and the well-stirred salt is treated with 1 cc. of 12 N hydrochloric acid for each gram of salt. After the acid has been added slowly through a dropping funnel, the solution is transferred to a continuous extractor (Note 4) and extracted with ether until no more malonic acid is obtained. The product, as obtained from the undried ether solution by concentration, filtration, and drying in the air, melts at 130° or higher and is sufficiently pure for most purposes. The yield is 415–440 g. (75–80 per cent of the theoretical amount).
This seems to take advantage of the fact that calcium salt of this dibasic acid is insoluble in water.
Whether this would bee true for the other acids produced is open to question. However, given their size it seems likely they would bee rather lipophilic and easy to remove with repeated nonpolar extractions.
Ning is coming to the strong belief that a home ozone generator is very handy to have around. With one, a bee could have almost unlimited amounts of malonic acid from electricity, air, and cooking oil. And that's just for this synthesis.
Even if one were not in the mood for barbiturates, malonic acid is good for making: Tropane (oooh, cocaine analogs) and cinnamic acids (benzaldehydes--> phenethylamines)
Ning hopes somebee is crazy enough to try this out. Who's the downer bee these days?