Author Topic: Phenethylamine via Leuckart  (Read 2507 times)

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psycosmo

  • Guest
Phenethylamine via Leuckart
« on: May 06, 2002, 10:40:00 PM »
Anybody see any reason why phenethylamine couldnt by made from phenylacetealdeyde use the Leukart Reaction with formamide and formic acid?

Rhodium

  • Guest
PhCH2CHO
« Reply #1 on: May 06, 2002, 11:40:00 PM »
Phenylacetaldehyde polymerizes easily, and the Leuckart reaction involves high temperatures and harsh reaction conditions, so it is very possible that the yield from such a reaction wouldn't be especially appealing.