Post 208698 (missing)
(Antoncho: "Re: Vilsmeier mechanism: the alternatives to POCl3", Chemistry Discourse), Antoncho says MCA is formed under reflux and in 'less vigorous' conditions, AC is the product. Any idea of what these 'conditions' are, Antoncho ? Anybody ?Patent GB211167 (http://l2.espacenet.com/dips/viewer?PN=GB211167&CY=gb&LG=en&DB=EPD)
claims it can be done with an 'excellent yield' of AA. However, after reading the patent a few times, I'm still having trouble figuring out exactly what makes their process give AA rather than AC or MCA.I suggest you stick to the S-and-Cl2 and Na acetate route described in that another (UTFSE) post of mine now archived on Rhodium's
I tried this and it appeared to work, although not very well. Where I deviated (yes I'm a deviant) from the method was allowing the decomposition of acetyl disulfide at atmospheric pressure rather than vacuum. So once I get my aspirator station behaving itself I'll try it again (and oh yeah I've got to make more NaOAc first..damn) which brings me to the other point,
By now constructing new equipment has beecome SWIM's second name - this not only develops one's imagination and technical and creative skills, but also makes life gradually more and more pleasant, as the said equipment accumulates and begins to pay back for the efforts spent in making it. Really.
I completely agree but by now my 'lab' is littered with the corpses of equipment that didn't quite work (H2 generators, Cl2 generators, vacuum devices, stirring devices, etc.) and I'd like something to work in simple glassware for a change.
Jeez this is turning into a very long dream...