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The Hive => Chemistry Discourse => Topic started by: java on July 08, 2004, 11:54:00 AM

Title: One Pot Conversion of amino acids to alcohols..
Post by: java on July 08, 2004, 11:54:00 AM
A Convenient One-Pot conversion of N-Protected Amino Acids and Peptide into Alcohols
George Kokotos

Synthesis 4, 299, 1990

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Abstract

N- Protected amino acids and peptides are converted to alcohols by chemoselective reduction of their corresponding mixed anhydrides with sodium borohydride in tetrehydrofuran with dropwise addition of methanol