hi there,
am trying to make some phenylpropanolamine.
Have attempted to reduce 2-nitro-1-phenyl-1-propanol with activated zinc catalyst / ammonium formate as in Post 370871 (https://www.thevespiary.org/talk/index.php?topic=12211.msg37087100#msg37087100)
(Barium: "2,4-dimethoxyphenylpropanolamine", Novel Discourse).
have failed at this twice now, achieving absolutely crappy yields.
I'm sure this can be sorted out in time, but not wishing to waste the last of my 2-nitro-1-phenyl-1-propanol, I wondered whether a reducing system that I am more familiar with would work.
Can anyone advise whether Red-Al or LAH would reduce the 2-nitro-1-phenyl-1-propanol to 2-amino-1-phenyl-1-propanol? If so then great, as I know how to do these reductions well.
Many thanks.