The Vespiary

The Hive => Novel Discourse => Topic started by: Lem on May 17, 2000, 12:43:00 AM

Title: Interesting Idea
Post by: Lem on May 17, 2000, 12:43:00 AM
Does anyone out there have enough biology background to be able to design a molecule that, when hit by MAO enzymes or other such system, would decompose into MDMA in the body, and would be synthable without going through any illegal substances? Would this substance be legal?

Title: Re: Interesting Idea
Post by: Chopper_ on May 17, 2000, 07:44:00 AM
Got no idea how to do that, but i do know that it most likely wouldnt be illegal.
During the prohibition of alcohol there were multiple compounds discovered that exist as solids and partially decompose upon hydration to give ethanol and another compound. These were not illegal (and could be sold i guess). I have no idea what these compounds were, but remember reading about them as a bit of trivia which came about during different areas of research. My guess is that they were never marketed (or used) because one of the decomposition products was toxic or had unwanted side effects. Research into the design of prodrugs (if it could be called one is this case) takes a lot of resources. Itd be a good excuse for a research grant if you could find a legit reason to do it, but id like to hear someone come up with one.

Title: Re: Interesting Idea
Post by: Rhodium on May 17, 2000, 11:02:00 PM
Sodium ethoxide? Upon contact with water, it is hydrolyzed to ethanol and lye. I wouldn't call that a "prodrug" though. You cannot eat sodium ethoxide.

http://rhodium.lycaeum.org (http://rhodium.lycaeum.org)

Title: Re: Interesting Idea
Post by: FILO on May 18, 2000, 01:43:00 AM
Sassafrass Tea?

Title: Re: Interesting Idea
Post by: Chopper_ on May 18, 2000, 03:08:00 AM
Youre right, im not sure if prodrug is the right word.
From memory, the structures of the compounds they made were quite large.

Title: Re: Interesting Idea
Post by: Rhodium on May 21, 2000, 10:32:00 PM
Trichloroethanol does not decompose to ethanol, but it is in itself active as a depressant, and in much lower quantities than ethanol.

http://rhodium.lycaeum.org (http://rhodium.lycaeum.org)