The Vespiary

The Hive => Chemicals & Equipment => Topic started by: moedank on June 30, 2003, 01:00:00 AM

Title: HELP! 4-mar synth, which PPA/norephedrine UTFSE
Post by: moedank on June 30, 2003, 01:00:00 AM

Ive read, printed every damn artical about the euphoria synth.  Spent 10 hours on this thing today(with the help of some sniff)
 
which one do i need

1)DL-Norephedrine hydrochloride
    DL-erythro-2-Amino-1-phenyl-1-propanol hydrochloride
  (±)-Phenylpropanolamine hydrochloride
 
2) L-(-)-Norephedrine
    purum, (1R,2S)-2-Amino-1-phenyl-1-propanol
 
3) D-(+)-Norephedrine hydrochloride
    purum, (1S,2R)-2-Amino-1-phenyl-1-propanol hydrochloride
   (+)-Phenylpropanolamine hydrochloride

Title: and im not really a stranger
Post by: moedank on June 30, 2003, 01:13:00 AM

I had the name moedank back in 2000, but didnt post much.  :P

Title: isomers
Post by: acid_egg on June 30, 2003, 02:17:00 AM

eleusis states-"It is interesting to note that all of the stereoisomers of 4-MAR are centrally active [1] (ie - it is not stereospecific in action)."

https://www.thevespiary.org/rhodium/Rhodium/chemistry/eleusis/aminorex.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/eleusis/aminorex.html)

However merck says that it is the (+-)-cis which are the drugs of abuse which I think rules out 2) or 3)(not sure which as I post)

Title: all of them
Post by: starlight on June 30, 2003, 10:45:00 AM

all of the above stereoismomers will work. What matters is that it is norephedrine.

Title: The most logical and economical choise would...
Post by: Bandil on June 30, 2003, 02:11:00 PM

The most logical and economical choise would definately be the -dl version as the optical pure versions often are quite expensive....

Title: thank you all and bandil
Post by: moedank on June 30, 2003, 04:55:00 PM

Thanks for that synth. write up you put on here.  changed my life.................

Title: molecule of the week
Post by: Jubrail on July 01, 2003, 12:58:00 AM

norephedrine is currently the molecule of the week on the ACS website  ;D

Title: still wondering!
Post by: moedank on July 03, 2003, 02:21:00 PM

I found this link

Post 352258 (https://www.thevespiary.org/talk/index.php?topic=9178.msg35225800#msg35225800)

(Rhodium: "The amide (trans-4-methyl-5-phenyl-oxazolid-2-one)", Methods Discourse)

but still am learning. Guess ill just try it and see!

Title: Well god said it would work
Post by: moedank on July 03, 2003, 05:51:00 PM

Ill let you know as soon as i can get some sleep......

Full write up of total non-chemist dream.  If swim high school chem teacher could see me now!  ;)

Title: meow
Post by: Vibrating_Lights on July 12, 2003, 12:27:00 AM

Title: I see now
Post by: moedank on July 12, 2003, 05:20:00 AM

hope youre right!

Title: hhhmmm
Post by: dumbjanitor on July 16, 2003, 09:09:00 PM

moedank, swims wondering, how difficult was this synth and how much serious chem knowlage is needed?

Title: Well how did it turn out moe?
Post by: Bandil on July 17, 2003, 01:58:00 AM

Well how did it turn out moe? Let us have all the greasy details ;)

Title: everyone calm down
Post by: moedank on July 17, 2003, 08:56:00 AM

SWIM heard about ICE the real one, 4mar so.........

SWIM saw the post about 4mar without the toxic gas route so they are gonna just make some.

in a dream SWIM looked long and hard for PPA but after ALOT of time spent found some under a rock.  In the dream he got the PPA in hand first then woke up.

Now he is dreaming about the set up and other chems needed.  All said and done now........but they aint sending it to him by email so it takes some time. ;)

Did you know the first ever organic synthisis used KOCN to produce urea, which is a common syn., and a good starting place for any organic chem.  8)

As soon as the guy comes down and sleepsshould bee about 2weeks) I will tell you the entire dream he had. dirty or not ;D

Title: well the dwarfs are all here so we are going...
Post by: moedank on July 30, 2003, 08:16:00 AM