How important are solvents? Can I just use less then is described in the procedures?
Say this one. Post 390003 (https://www.thevespiary.org/talk/index.php?topic=12782.msg39000300#msg39000300)
(flipper: "LSD from LSA synth qeustion", Tryptamine Chemistry) Carbodiimidazole method.
If swim want to make a batch of 1 kilogram he needs to use almost 100 liters of DMF. That's a lot of solvent.
But can swim use say 50 liters of DMF or THF or Chloroform in this reaction without effecting the yield? ::)