Hey bees swim has few questions before swim tries the Iodosafrole route to mda/mdma. The halogenation is fine; swim will use the NaI in DMSO + H3PO4 to make HI and gas the chilled safrole as it says in the doc for halo safrole on rhodium’s pages.
#1 is the DMSO still required when using phosphoric instead of H2SO4? DMSO was mentioned on rhodium’s halo safrole docs when using H2SO4 as it has the habit of making iodine in this process, phosphoric wont do this will it?? Swim is using a gas generator instead of putting it into the safrole, and piping the gas ala HCl gassing at the end.
#2 the HI gas (Oh Oh), how can swim pipe it? Swim has visions of any kind of tubing disintegrating on contact and swim getting lovely acid burns over 90% of swim’s body, but is swim wrong? Can tubing take it?
Swim is making methylamine.HCl ala hexamine, HCl and water, then dropping this into the Iodosafrole and reflux, this part is fine in practise but….
#3 Swim has found in organic chem text swim had lying around that amination of halides (does not specify primary of secondary) with secondary amines does not stop after one run, ie: The MeNH2 will goto MDMA then the nitrogen will kick off another hydrogen and grab another Iodosafrole, making a monster compound consisting of two methoxy’s hooked to the one nitrogen making a tertiary amine compound.
? RHODIUM, BRIGHTSTAR, ANYONE, HELP!!!!
Can someone confirm/deny this? and give swim options for a way to stop it doing this??? swim was thinking that changing the order of addition; add the iodo to the amine may work to reducing this product being formed?
Or is it that this happens only with primary halides and not our beloved secondary halide?
The rest of the process is well documented; swim is ok with the next parts.
If swim is happy with the method after some bees re-assure swim with answers to the questions then swim is going to be doing a photo assay and full write up with yields to share with the hive on this process. Please if swim has mistaken anything or left something out tell swim and swim can post it.
POKE HOLES IN SWIM’S METHOD IF THERE IS ANYTHING WRONG PLEASE!!! Rather it is wrong on paper than in practise, also swim has looked on TFSE and found nothing concrete, seems to be a lot of confusion re Iodosafrole.
Swim thanks all bees who help.