Author Topic: Quick oxygen/wacker in almost 80% yield?  (Read 1735 times)

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OcoteaCymbarum

  • Guest
Quick oxygen/wacker in almost 80% yield?
« on: May 09, 2004, 08:47:00 PM »
I was reading a prep on Organic syntheses about a wacker-type of oxidation and the easiness and the yields just seem great

Basically, using 32 grams of CuCl2 and 1.19 grams of PdCl2, the author claims a 78% yield on 1.66 moles of alkene.
The starting compound is 2,2 dimethyl-4-pentenal and the end product the corresponding methylketone.

http://www.orgsyn.org/orgsyn/prep.asp?rxntypeid=192&prep=CV8P0208



As anyone ever tried something similar? Imagine the yields being the same for our favorite alkene...

XrLeap

  • Guest
this seems to be fairly easy, but processing...
« Reply #1 on: August 12, 2004, 10:45:00 PM »
this seems to be fairly easy, but processing time of 60 ro 66 hr is long, isn't it?


OcoteaCymbarum

  • Guest
Would you care if it gave such high yields?
« Reply #2 on: August 13, 2004, 07:01:00 AM »
I know I wouldnt.
Using 1.19 grams of Palladium to transform about 270 grams of safrole into 230 grams of ketone, I wouldnt care about those 60 hours.
What I really wonder about is oxygen flow. They dont mention it anywhere, its the drawback I find. So its seems its really a matter of how much oxygen needs to be used.

I had totally forgotten about this post, I realize the title of thread is not right.

Rhodium

  • Guest
Then what about this variation?
« Reply #3 on: August 13, 2004, 09:15:00 AM »

Post 417436 (missing)

(Rhodium: "Wacker with 80% yield in 10minĀ  at RT with less Pd", Novel Discourse)