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#128 Methyl-J MBDB

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Rhodium:
Post 454922 (missing) (Rhodium: "Always* use Toluene instead of Benzene", Newbee Forum)

tryin:
Little by little I hope I am getting this.

Reading the synthesis of P2P on Rhodium, I saw this iron/acid reduction:

Reduction with Iron Powder

If phenyl-2-nitropropene is reduced by iron powder in an acidic medium (such as acetic acid or aqueous hydrochloric acid) the nitroalkene is reduced to the oxime, which is then hydrolyzed by the acid into the desired phenyl-2-propanone.

Phenyl-2-nitropropene (10 g, 61 mmol) was dissolved in 75 ml HOAc and slowly dripped into a refluxing slurry of Fe powder (32 g, 0.57 mol) in 140 ml HOAc. The mixture turned brownish and foamy, and the mixture was refluxed on low heat for 1.5 h. The reaction mixture was poured into 2000ml water, and was extracted with 3x100 ml CH2Cl2. The combined extracts was washed with 2x150 ml H2O and dried over MgSO4. The solvent was distilled off, and the residue distilled under vacuum to give phenyl-2-propanone in 75% yield.

Is this iron/acid reduction the same one that Shulgin talks about in the preparation of 1-(3,4-methylenedioxyphenyl)-2-butanone from 1-(3,4-methylenedioxyphenyl)-2-nitro-1-butene?
(can be found @ end of third paragraph for #94-J)

Could I also use Methyl Man's Al/Hg + Nitromethane method for the reduction of 1-(3,4-methylenedioxyphenyl)-2-nitro-1-butene __> 1-(3,4-methylenedioxyphenyl)-2-butanone?

indole_amine:
about 1): Yes (without checking; but in PiHKAL, Shulgin definitely makes use of the same method to convert phenylnitroalkenes to their ketones)

about 2): no, MeNO2 Al/Hg is a reductive amination to arrive at methylated amines, read honey. The Al amalgam reduces the nitromethane to methylamine, which condenses with the ketone to give an intermediate methylimine. This is reduced to the methylamine (honey) by aluminum amalgam, too. Al/Hg has nothing in common with Fe/HCl, except both have great reducing power and therefore both reactions are reductions. But nitromethane has no use in Fe/HCl reductions.

(side note: maybe Al could be useful with Fe/HCl. Additional hydrogen maybe? Does anyone know?)


indole_amine

somuchclass:
MBDB was, until recently, available on the mail order internet research chemical scene.  I have heard a user of it describe the effects as a quote, "psychedelic quaalude."  Others noted that MBDB lack all stimulant properties associated with the amphetamines and, albeit less so, with MDMA.

tryin:
In the preparation of 3,4-Methylenedioxyphenyl-2-nitro-1-butene found here Post 103792 (Rhodium: "3,4-Methylenedioxyphenyl-2-nitro-1-butene", Chemistry Discourse) Could one use Ammonium acetate instead of n-butylamine as the catalyst?

If so what would be the ratio?

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