The Vespiary

The Hive => Newbee Forum => Topic started by: Gravimetric on July 05, 2004, 01:13:00 PM

Title: Codeine extraction from soluble tablets
Post by: Gravimetric on July 05, 2004, 01:13:00 PM

I UTFSE but to no avail WRT soluble tablets. Its a very basic question, even for the "Newbee forum"....

Having read

https://www.thevespiary.org/rhodium/Rhodium/chemistry/codeine.chromic.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/codeine.chromic.html)

the process of seperating codeine and caffeine seems pretty simplistic. However, due to "ease of procurement", I am thinking of using tablets which are soluble. They contain 500mg paracetamol, 30mg caffeine and 8mg codeine each. The scale would be involving 3~5g of codeine, so several hundred tablets.
Would just using a smaller amount of water be enough, to prevent whatever mechanism they use to dissolve the paracetamol from working, or would there be need for a more complex extraction, such as the acid/base method talked of here :

Post 499961 (https://www.thevespiary.org/talk/index.php?topic=5771.msg49996100#msg49996100)

(BieneMaya: "have a look at this", Chemicals & Equipment) .
I've done CWE before but not on soluble tablets. If push comes to shove I can use the non-soluble brands but they come in smaller quantities, so more hassle getting enough packets to be practical.

Thanks :)

Title: research
Post by: BieneMaya on July 06, 2004, 02:20:00 PM

Here you will find your answer....

http://codeine.50g.com/info/extraction.html (http://codeine.50g.com/info/extraction.html)

Title: Hmm....seems it doesn't give a method but...
Post by: Gravimetric on July 07, 2004, 01:55:00 PM

Hmm....seems it doesn't give a method but rather "Don't bother with dissolvable tablets" :(

To make things simpler I'll just go with non-soluble tablets which removes the problem of caffeine too. Just got get some Sodium Carbonate to do the chloroform extraction to get a decent yield. It'll be fiddly enough with all those tablets.

Thanks :)

Title: expected yeilds
Post by: JewishNazi on July 08, 2004, 08:54:00 PM

gday, im hoping to do the same thing in a couple of days. I recently aquired 200 - 8mg codeine phosphate tablets for AUS$28.60. Is that a good price and what yields i should expect