Post 48274 (missing)
(poppystraw: "Re: morphine sulfate to heroin hcl", General Discourse)Post 209556 (missing)
(taig: "morphine sulfat -> morphine hcl", Newbee Forum)https://www.thevespiary.org/rhodium/Rhodium/chemistry/morphextr.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/morphextr.html)
)Post 459880 (missing)
(reallyserious: "morphine sulfate to its base or HCL", General Discourse)1. Dissolve crushed pills in minimum amount of distilled water. Filter with a buchner funnel, keep the solution and discard the remaining pill binder. Add aqueous ammonia (strength isn't important, 5% is good), take the pH up to about 10 or until the freebase has clearly precipitated.
I've tried this sever times with lots of 3 to 30grams of MSIR .1K to 1K pills again content of pills is 30 mg they weight about 44mg (buffer lactose/surcrous. I've getting a very small yield
from step one. And based on the following I should not even need to go on to step 2 (the toluene/
butanol) based on post by morphine90cc:
morphine sulfate to heroin hcl
Morphine 90cc
If you wish to convert the morphine sulfate to heroin you must convert the acid salt (morphine sulfate) to its free base.....this is accomplished by first disolving the morphine fron the pills in distilled water, minimum amount....filter using buchner funnel...next very carefully add ammonium hydroxide(dilute soln.) in excess to the mother liquoid...vigorously shaking....a white precipitate is formed....cool the soln in the refrigerator over night to allow maximum crystal growth...filter using buchner.....sometimes reducing the amount of mother liquid is helpful to obtain more crystals of morphine..cool and filter again....the resulting white powder is morphine free base...the above procedure works for the acetate, hydrochloride, and sulfate salts of morphine.....this freebasing procedure is a good source for morphine base however it takes about 100 pills @ 10mg morphine to produce 1000mg of morphine base...one gram...
The tartaric acid purification procedure is used whenever very pure morphine base is required...generally this methid is used when recovering morphine base from poppy straw extract which contains a variety of plant alkaloids...and separation of simular compounds is difficult.....
which is what I think your suggesting, just is not working. At least not how I'm doing it.
a white precipitate is formed....cool the soln in the refrigerator over night to allow maximum crystal growth
I'm getting a 5 to 10% yield, and no "crystal growth" occurs at all with cooling and time, infact
what does precipitate at T= 5-20 minutes tends desolves back into the solution.
It stated
sometimes reducing the amount of mother liquid is helpful to obtain more crystals of morphine
I an effort to keep the mother liquid as pure as possible my mistake could be that the pill to H2O mixture to too low, the pill matter left behind in the buchner funnel which is abudent and still contains quite a bit morphine, my concern is that the MSIR pill which is M + H2SO4 + 5H2O, is not desolving at the same rates, I obtain a mother liquid which is about 80 ml after filtering (80ml H2O to 10-20g of MSIR.)
Should I be using a higher ratio of H2O to MSIR?
Ideally I should have very little pill matter left behind in fact if it were possible all I would
want in the filter is the 14mg of lactose/surcrouse per pill.
Its probably that simple but I have taken the time to calculate everything: the MSIR pills
are 764.878g/mol of that about 12% is H2SO4, equilivency for H2SO4 is 2:1 when mixing with
NH4OH ( NH3+ H2O-) my goal was to completely nutralize the acid.
Reallyserious
poppystraw:
2) next extract morphine base from aqueous environment with toluene/butanol mixture.....if the morphine base is contaminated with other materials....ususally one checks the melting point to determine purity...if M.Pt is low use the toluene/butanol mixture 1:1 ratio...if the melting point is sharp skip the purification step
3) precipitate as tartaric acid (important purification step)
4) finally convert tartrate to free base then use acetic anhydride to convert the morphine free base to heroin,then convert the heroin base to the HCl or sulfate salt
Morphine Sulfate vs. Morphine HCl
So I will then add 5% HCL to convert to it hydrochloride, much like “desox” outlined
below. so then I will finally be ready to get back and proceed with acetylating using
AA. Another side note: The only benifit I see in using 4DMAP is faster acetalation
time. If I let it reflux @ so 90 to 100C for 3+ hours I should get the same effect. And
then you have to get the DMAP out. Although I can’t explain why we get such a high
peak at 5.15 min with 4-DMAP with a little one at 4.40 which is the 3-actelylmorphine. I
understand that the 4-DMAP is acting as a catalyst, my question is with time won’t all the
3-Acetyalmorphine complete its acetalating to form 6-acetalymorphine?
So
1. Which is prefered NaOH or NH4OH?
2. what is the true benifit of 4DMAP?
I'm convinced that I had too concentradted solution
Here is a post from EROWID's site by Desox FYI:
Morphine
by desox
--------------------------------------------------------------------------------
DOSE : T+ 0:00 20 mg insufflated Morphine (powder / crystals)
T+ 2:30 10 mg insufflated Morphine (powder / crystals)
BODY WEIGHT : 80 kg
After my experiences with snorting crushed up morphine sulfate pills, which were quite disappointing, I asked a friend why nothing really had happened. He told me snorting sulfate salts doesn't work well, since sulfates aren't that good water-soluble and I should change the morphine sulfate to morphine hcl, which is suitable for snorting.
[edit: I checked that solubility matter and it turned out that morphine sulfate is even better soluble in water than the hydrochloride... So to be honest, I have no clue why the crushed pills did barely anything good. Lately I tried them again and they worked just as fine as the hcl.]
I did so and ended up with about 300mg of pure morphine hcl powder. I divided the powder in 15 parts, 20mg each and snorted one of those little bumps. First thing I felt was a burning sensation in my nose, worse than that you get from meth. I was waiting for the effects to begin, but nothing really happened and I was getting disappointed, but then suddenly after 10mins the effects started to kick in.
This gave me a really nice feeling, that typical opiate high. You get relaxed, a little bit euphoric and don't care about nothing. I just sat down, read some magazines, listened to music and watched TV. I snorted the first bump at about 8pm and at 10:30pm I decided to do another little bump to intensify the feelings. I devided one of the 20mg bumps in two and snorted that. This time there were absolutely no pain, I wonder why? :) I continued reading, listening to music and watching TV for a few hours until 3am. Then I went to bed, had that dreamlike state I use to get when trying to sleep on opiates and finally felt asleep at 5am.
The conclusion is, that when you come across some morphine pills, which all are morphine sf, extract the morphine, change it to the HCl salt and snort it. Eating is a terrible waste (I need 80mg oral, but only 30mg nasal) so if you're not into IV'ing snort it.
Extraction is easy:
1) Dissolve crushed pills in water
2) _Slowly_ add _little_ drops of an NaOH solution until the water reaches pH 9. Be sure not to add too much, because then the extraction fails and nothing happens.
3) At pH 9 crystals should fall off, forming a clowd in the water. Put the glass in the freezer for about 10mins and filter out the crystals after that.
What you now have is pure morphine freebase. Changing to HCl salt is easy, too:
1) Dissolve in anhydrous (99%) alcohol.
2) Add 1ml of HCl and shake.
3) Let the alcohol evaporate (do NOT boil!) and you'll have some nice morphine hcl crystals.
4) Have fun.
Exp Year: 2001 ID: 10234
Added: Oct 27, 2001 Views: 10778