J. Am. Chem. Soc. 113(24), 9286-9292 (1991) (https://www.thevespiary.org/rhodium/Rhodium/pdf/cocaine.biosynthetic.pathway.pdf)
(https://www.thevespiary.org/rhodium/Rhodium/pdf/cocaine.biosynthetic.pathway.pdf)
Epherdrine producing method by using large-scale ephedra cell culture as material
Patent Number: CN1256316
Publication date: 2000-06-14
Inventor(s): CHA LIHANG (CN); JIAO YUXIA (CN); LIU DALU (CN)
Applicant(s):: INST OF CHEMICAL METALLURG CHI (CN)
Requested Patent: CN1256316
Application Number: CN19980125186 19981204
Priority Number(s): CN19980125186 19981204
IPC Classification: C12P13/00
EC Classification:
EC Classification:
Equivalents: CN1077600B
Abstract
The present invention relates to the method of producing ephedrine by using large-scale ephedra cell ZHJ-25 CGMCC No.0359 culture as raw material. Ephedra cell ZHJ-25 CGMCC No.0359 is inoculated intosugar containing culture medium through three ways, and cultured in 25 +/- 2 deg.C for 20-50 days before the culture is dried at 60 deg.C to obtain ephedrine-containing raw material. The method is simple, may be used in continuous or semi-continuous industrial production of ephedrine in high yield and the product has stable ephedrine content.
Not so easy to get hold of as they also invented the spelling of ephedrine new.
All in all this might be a considerable pathway to many beloved compounds.
Not for those who are always in a hurry.
If anybody has seen something similar as patent - not written in chinese/japanese, I would be very appreciated to get a hint.
thanks
ORGY
Post 295082 (https://www.thevespiary.org/talk/index.php?topic=11402.msg29508200#msg29508200)
(Rhodium: "Cocaine biosynthetic pathway", Novel Discourse) in this thread, I have updated it with a picture of the biosynthetic pathway, as well as a link to the article in question.Org. Lett., 2(1), 3-5 (2000) (https://www.thevespiary.org/rhodium/Rhodium/pdf/cocaine.biosynth.n-methylputrescine.pdf)
(https://www.thevespiary.org/rhodium/Rhodium/pdf/cocaine.biosynth.n-methylputrescine.pdf)10.1021/ol990940s (http://dx.doi.org/10.1021/ol990940s)