Author Topic: Strong acids in CTH of mandelonitrile acetyl ester  (Read 1301 times)

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psygn

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Strong acids in CTH of mandelonitrile acetyl ester
« on: December 09, 2002, 07:27:00 AM »
Why do strong acids/elemental H2 seem to bee necessary in the CTH of mandelonitriles and their esters? What would bee the product of a CTH w/HCOOK + Pd performed on a mandelonitrile ester? Amine? Nitrile? No rxn?

What about CTH w/H2 generated in situ from NaBH4 w/ a strong acid?

Many thanks,
-psygn