Best way for an rP/I2 reaction, IMHO, is the long wet reflux. I recommend 1:1.2:0.5:0.8 ratios E:I:P:H2O, assuming lab grade materials. I suggest refluxing at an in-flask temperature of just under 100C for thirty six hours. I no longer follow Placebo's method. I have followed it in the past. I works, it produces good methamphetamine. It is not as foolproof or forgiving of errors as a wet reflux, IMO, and the wet reflux will give you excellent yield of high quality meth regardless of your experience with the synth. You do not need to add sodium thiosulphate at the end to clear iodine; a short boil of the open flask after the reaction to remove volatile inactives and a few nonpolar washes of the reaction fluid, in particular with the solvent chosen to extract the meth, are recommended. Basing the reaction fluid will take care of any free iodine still in the fluid.
The reaction will be complete by 36 hours. Experience will give you a feel for telling that the reaction is done, and smell and visual cues that are observable after the flask cools at the end of the reaction will tell you that it is finished. These are difficult to describe to someone who is not familiar with the reaction. Fortunately, you will not need to know the smell or the visual cues, you merely need to keep track of the time.
All of this information is available with little effort by the use of the search engine. Most of it can be found in the digest thread at the start of the stimulants forum. I have taken the time to answer most of your questions because I am an advocate of the long wet reflux, and in particular recommend that persons who are not familiar with this synth begin by doing it rather than the dryer, faster reactions. I have found the learning curve for the LWR to be very short, and the chance of quick success much higher than the with the other methods.
Many more details are available in the threads and I urge you to take the time to read them and learn more about the reaction before you attempt it.
