Author Topic: One Pot Conversion of amino acids to alcohols..  (Read 2394 times)

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One Pot Conversion of amino acids to alcohols..
« on: July 08, 2004, 11:54:00 AM »
A Convenient One-Pot conversion of N-Protected Amino Acids and Peptide into Alcohols
George Kokotos

Synthesis 4, 299, 1990



Abstract

N- Protected amino acids and peptides are converted to alcohols by chemoselective reduction of their corresponding mixed anhydrides with sodium borohydride in tetrehydrofuran with dropwise addition of methanol