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Why don't you post some selective reduction methods
with references which are better than the procedures from my page which you trashed in another post of yours, instead of just writing small non-informative comments here and there?
Stereochemistry of the Reduction of Tropinone to Tropine/PseudotropineI'll begin with posting two landmark articles on the stereoselective reduction of tropinone in high yield, the ratios between tropine/pseudotropine being anything from 2:1 to 1:9 depending on the reaction conditions. Over three dozen reducing systems were evaluated, including NaBH
4/LiBH
4/KBH
4 (in water or alcohols), LiAlH
4 (in ether or THF), Sodium in toluene or alcohols, and Al(i-PrO)
3 in i-PrOH. They also equilibrate either tropine or pseudotropine using either of the two latter (reversible) systems, and measure where the equilibrium point between the alcohols lie in different solvent systems.
Reduction of TropinoneA. H. Beckett et. al. Chemistry and Industry, p. 663 (1957)
(
https://www.thevespiary.org/rhodium/Rhodium/djvu/tropinone.reduction-2.djvu)
Stereochemistry of the Reduction of TropinoneA. H. Beckett et. al. Tetrahedron, Vol. 6, pp. 319-330 (1959)
(
https://www.thevespiary.org/rhodium/Rhodium/djvu/tropinone.reduction-1.djvu)
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DjVu Browser Plug-in v4.1
(
http://www.lizardtech.com/download/?x=2&p=1&o=1&titl=Download%20DjVu%20Browser%20Plug-in)