The Vespiary
The Hive => Chemistry Discourse => Topic started by: Aurelius on July 14, 2003, 11:18:00 AM
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What would happen to this compound upon Claissen Rearrangment? the possibility of a usable compound from gakk sparked my interest.
Post 414593 (missing)
(badbody: "Guaifenesin", Stimulants)
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You can only perform Claisen Rearrangements on allylic ethers. Guaifenesin has no aliphatic double bond anywhere, so it won't react that way.
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Dehydration.
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Well, in the case it was first dehydrated to the allyl ether, the major product would be 2-hydroxy-3-methoxy-allylbenzene (I doubt that would be usable) and the minor product would be eugenol...
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It was worth a shot. I just looked at that molecule and said " hey, it'd be great if they handed us precursors." But alas, it was not to be.
oh well.