chem.lett. - 1984 - 1509/1510alpha iodopropanoic acid (brief summary, read the 2 page .djvu!)
CuCl (0.5 mol equiv), CuCl
2 (0.5 mol equiv), I
2(1 mol equiv) and propanoic acid (excess) are mixed and reacted at 120°C for 6h under N
2 atmosphere. Precipitated copper salts are filtered, excess acid is distilled off, product is recrystallized from hexane to afford a 90% yield based on I
2.
where to go from here ?Post 212002
(Rhodium: "Easy nitroethane in quantitative yield", Methods Discourse)Post 333551
(Barium: "benzaldehydes to phenylacetones", Novel Discourse) w/the corresponding alkyl esters; prep. of methyl ester: J.Org.Chem.; 45; 14; 1980; 2831-2834.
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psyloxy--