Hey Bees,
Long time listener, first time caller… or something,
Anyway, I have a couple questions that I can’t find the answer to with TFSE.
First, If one was to dream about a MeOH/p-benz wacker, how would one know it was done? MM says over 9 hrs, BS(in dmf) says 7.5+. Has anybee run spots on this rxn?
It seems that the reflux of CH3OH is a more repeatable and standard condition then BS/Strikes “room temp”. Anyway, Is this 1 hr. addition plus 8hrs. reflux just some bees guess at long enough?
Are there visual clues to the reactions progression?
If one was interested in running spots, since it’s already in MeOH, could we assume this to be acceptable for the chromatography as well?
How about Al amalgam! I keep reading about bees using millings, filings and turnings. Now how are these bees assuring that the Al is pure and not an alloy? All the shops that I have ever been to machine all sorts of alloys on the same machines. Most of the Al used is some sort of alloy. Does this addional copper/mangonese/WTF ever mess with the reaction/amalgamation? Is this one of the secret reasons for the numbers of failures and low yields?
If one was interested in playing around with Al/Hg and Nitromethane(and thicker Al with a reflux and overhead stirring), why wouldn’t one want to reduce the nitro first? Seems to Sh0rtTerm that bees would want the MDP2P addition to be like Fred Durst jumping in the playboy grotto full of drunk, wet playmates. Sexy amine everywhere, ready to hook up!
Oh, while nobee is reading this anyway, has the washes of sassafras prior to distilling fallen out of favor for any specific reason? If my memory was better I would probably be thinking about NaOH removing eugenol or some such shit. Was that all just hype, or are we to be assumed incapable of washes/emulsions and fractional distillation?