Author Topic: P2P again  (Read 2547 times)

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obituary

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P2P again
« on: August 15, 2001, 03:52:00 AM »
another way to P2P

Letts Nitrile synthesis: ref: chem rev. 42, 264 (1948)

RCOOH + KSCN -heat-> RCN + KHS + CO2

use phenylacetic acid to get it's respective nitrile- or obtain it by other measures. 

now you have the nitrile.

nitrile + MeMgBr --> imine --acid--> P2P 


Rhodium

  • Guest
Re: P2P again
« Reply #1 on: August 15, 2001, 11:56:00 AM »
Can R be aromatic as well as aliphatic?

obituary

  • Guest
Re: P2P again
« Reply #2 on: August 15, 2001, 04:36:00 PM »
that obit hasn't figured out yet, definitely aliphatic, maybe aromatic.  can't seem to find anything other than that one reference.  haven't had time to look up the actual ref yet either.  if somebody would search for some info on it, obit would be greatly appreciative.  (P-Sam, master searcher, please)