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Question on reductions using LAH

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LeVogue:
I've noticed many individuals who chooses alternative methods for reductions of nitropropenes/styrenes rather than Shulgins favorite (high-yielding) method with LAH.

I know it can be a problem to obtain LAH, but a guy i saw on TV bought some, and now he's thinking about just forgetting the whole thing and pick another method to reduce his P2NP to Amphetamine.

Is it really that hard/dangerous to work with, or would there be a chance that the guy could move on without any fear and reflux his nitropropene with it ?

Maybe someone who knows the chemical could explain a few things about reductions with LAH. Personally i'm sure that the guy from TV could use some information on where the common mistakes are made.


-Le Vogue

Rhodium:
This contains some valuable advice:

http://rhodium.lycaeum.org/chemistry/eleusis/zwit.2c-h.html

Main points: Use Sodium-dried solvents, add the nitrostyrene solution SLOWLY, and make sure you use a dust mask so you dont inhale any of the very fine LAH dust, which easily disperses into the air.


http://rhodium.lycaeum.org

foxy2:
Why not save the LAH for something more interesting?
You could reduce the P2NP with one of the lower yeilding methods.
Shit you could reduce phenylalanine with the LAH to amphetamine and you would end up with more.

Do Your Part To Win The War

yellium:
Sodium drying of THF (with benzophenone as indicator) is not recommended for quick&dirty work. Takes way to long, and when the Na has done its job after 2 days then you need to distill your THF.  Of course, if you work in a real lab, you can make a dedicated THF drying setup, just like the pros.

For me, drying your (not-to-wet) THF or ether with CaSO4, and then adding slightly more LAH also does the job. Another quick&dirty way is adding NaH (if you can get that) to your THF until it doesn't fiz anymore. Let it stand for a while, decant of the amount of THF you want to use onto your LAH...presto!

Dust mask? Nah. Gloves.

OTOH: LAH for amph? I would save it for 2C-B. Unless you don't like visual drugs.

Yellium `I love the smell of bromine in the evening'

terbium:
Re Post 63698 (missing) (LeVogue: "LAH to acetic acid ester of eph", Newbee Forum) . The guy on TV should take his LAH out of the fridge and let warm to room temp. before opening the can. Don't want any moisture condensing on the LAH.

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