The Vespiary

The Hive => Novel Discourse => Topic started by: pHarmacist on May 11, 2003, 10:19:00 PM

Title: Oxidation of Amines using Benzoyl peroxide
Post by: pHarmacist on May 11, 2003, 10:19:00 PM

Improved Oxidation of Amines with Dibenzoyl Peroxide

Full-text:

http://pharmacist8.tripod.com/OH-amines.pdf (http://pharmacist8.tripod.com/OH-amines.pdf)

Barium  ;)

Title: FLEA
Post by: pHarmacist on May 11, 2003, 10:56:00 PM

Shulgin prepares FLEA from MDOH, now, it can also effectively bee prepared from MDMA.

See:

http://www.erowid.org/library/books_online/pihkal/pihkal081.shtml (http://www.erowid.org/library/books_online/pihkal/pihkal081.shtml)

Title: noh amines from amines
Post by: obia on May 12, 2003, 11:23:00 PM

from memory there is also a series of papers by Beckett which describe the oxidation of primary and secondary amines to the corresponding azanol. his method uses MCPBA metachloroperbenzoic acid followed by hydrolysis. unfortunately all these oxidation routes require preparation of the illegal amine and if you are going to prepare the amine why not just stop there and eat it, flea is not as interesting as its amine parent.
what is really needed is a route to produce an O substituted oxime (or perhaps a N-substituted nitrone) reduce to the o/n substituted hydroxyamine and then remove the o protection. at least that way if the reduction proceeds too far you don't end up with an illegal amine.