along the same lines there are other things that can increase alkaloid production (in one of theses ergot threads around here, ill dig it up later).
Also, as far as the time frame to maturity of claviceps, im not sure that i understand your issue...as far as fungus goes thats pretty fast, and i sincerely doubt that an lsd cook would have any trouble waiting for that period of time. Also, the amounts of micrograms youre talking about is way more than i think most of us had in mind....i think even the Gambino family would have problems distributing that much acid.
but kudos on the tryptophan ideas...there is absolutely no reason why we shouldnt explore all possibilities thoroghly.
EDIT: here ya go.
Post 246873 (https://www.thevespiary.org/talk/index.php?topic=12792.msg24687300#msg24687300)
(bujinkan: "Re: ergot and agar", Tryptamine Chemistry)
The yeild of lysergic acid and its derivs. is enhanced by using Claviceps Paspali NRRL 3027 mutants as the fermenting organism. Such mutants are obtained by subjecting the microorganism to x-rays and or UV radiations and or ethyleneimine treatment.
I was checking out some old articles I hadn't looked at recently (because they are in German). Kind of a gem, at least as regards the topic of this thread: Stoll, Rutschmann & Petrzilka, Helvetica Chimica Acta 33, 2257-2261 (1950), "Über Derivate des 1,3,4,5-Tetrahydro-benz(cd)indols."
Here we have "Uhle's aminoketone", in hydrochloride and acetamide form, a year before Uhle ever published making a derivative of it, so I will swiftly make a mental note to adopt the name "Stoll's aminoketone" if writing further on these subjects.
Okay, so it's unstable as hell in freebase form, but stable in hydrochloride and N-acylated form, i.e., no different from the indoline analogue prepared by Kornfeld (Woodward) et al. ( https://www.thevespiary.org/rhodium/Rhodium/pdf/lysergic.acid.woodward.pdf (https://www.thevespiary.org/rhodium/Rhodium/pdf/lysergic.acid.woodward.pdf)
page 3090). I still think it's worth a look-see. Also answers almost all worries whether the structure could survive conditions of intramolecular Knoevenagel (Stobbe) condensation and similar active methylene reactions. The "6,7-imine"-analogue sure does using potassium butoxide, giving a nice Keller-reaction afterwards.
The article mentioned in Post 401117 (https://www.thevespiary.org/talk/index.php?topic=12599.msg40111700#msg40111700)
(bottleneck: "On the notion of using an azlactone of an...", Tryptamine Chemistry) can be read at https://www.thevespiary.org/rhodium/Rhodium/chemistry/elymoclavine.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/elymoclavine.html)