The Vespiary

The Hive => Chemistry Discourse => Topic started by: FriendlyFinger on January 21, 2003, 02:40:00 AM

Title: Getting rid of Butal-OH from Methylamine?
Post by: FriendlyFinger on January 21, 2003, 02:40:00 AM

Hi there,

Is it a good idea to rinse methylamine.Hcl with acetone after recrystalisation with Butal alcohol? Will any leftover alcohol interfere with Al/Hg or Borohydride reductions?

Mayby I need to vacuum dessicate longer. I can't stand that Butal stench. Always knocks me out when opening the dessicator.

Thanks,
FF.

Title: BuOH
Post by: Rhodium on January 21, 2003, 05:21:00 AM

Instead of acetone, wash with ether, CH₂Cl₂ or CHCl₃. MeNH₂.HCl is both inert to and insoluble in them all.

Acetone may form an imine with MeNH₂.HCl so I don't reccommend that. Aside from smelling bad, butanol won't interfer the reductive amination.