The Vespiary

The Hive => Chemistry Discourse => Topic started by: Kefka on July 22, 2004, 12:51:00 PM

Title: freebasing compounds
Post by: Kefka on July 22, 2004, 12:51:00 PM

how would someone go about removing a compound from its base(such as hydrochloride or hydrobromide)?

Title: Neutralise it with a strong base, then extract
Post by: KidCurry on July 22, 2004, 01:07:00 PM

Neutralise it with a strong base, then extract with non-polar solvent and do the usual work-up. You might also consider using the search engine, this topic has been covered many times before.
And your question is strangely formulated.

Title: Easiest method is to dissolve the compound in...
Post by: SpicyBrown on July 23, 2004, 06:18:00 AM

Easiest method is to dissolve the compound in methanol, assuming it's soluble, then add KOH dissolved in methanol. KCl will precipitate out. Filter, rinse filtered solids with additional methanol, evaporate and be done with it.

Of course, if the compound you're freebasing is sensitive to strong bases, you'd want to go a different route...

-SpicyBrown