Alright, I'll admit it. I can find no comfortale source of sassy. It's just too fuckin' scary for me now. So what am I gonna do? I'm gonna find another way of making MDMA. I have seen several ways to do it, and I haven't seen too many appealing ones. There's the neverending eugenol-->safrole synths, but frankly, I just don't give a fuck anymore. It seems to me like it's just one more step that will have to be done, and as of yet, no one has come up with anything but low yeilding steps.
The only thing I can think of is synthing MDP2P from catechol, after methylation to 1,3 benzodioxole. I don't want to synth safrole, because that's just added steps. I'm looking for a synth that doesn't go through safrole, and has the least amount of steps as possible.
The one that keeps sticking in my head is the grignard reaction on benzyl chloride using acetonitrile, resulting in P2P after hydrolysis.
https://www.thevespiary.org/rhodium/Rhodium/chemistry/phenylacetone.html#ephedrine
https://www.thevespiary.org/rhodium/Rhodium/chemistry/grignardnitrile.html
I think that if the reaction works as advertised, it means just three steps from catechol to MDP2P, with methylation and then chloromethylation.
[url=https://www.thevespiary.org/talk/index.php?topic=7047.msg32129100#msg32129100]Post 321291
(Antoncho: "An interesting chloromethylation procedure", Chemistry Discourse)I didn't think that this could be a viable production synth, though, because of the grignard angle. I don't think that grignards are a real option for most clandestine labs, given the fact that everything has to be very anhydrous, or the whole thing fails. It might not be that bad for a small batch, but think of the risk of trying to put out a batch of over 500g. IMHO, there's just too much risk of a failed reaction. I just wouldn't take the risk.
But after I read
Post 346231
(Antoncho: "Zealot: a new zincorganic synthesis of P2P's", Novel Discourse), I thought that this might be a very viable option. Now, what are everyone's opinions on this reaction? I remember someone mentioning that other reagents besides acetonitrile can be used to get the P2P, is that correct? Does this reaction actually work? Has anyone actually tried it?
It is seductive, way too seductive. -Eleusis