Subject: Distilling toluene
Yes, if the imine was formed in toluene, you distill off most of it and then dilute the residue with a suitable amount of methanol to make a toluene-containing methanolic solution of the imine. Toluene and methanol are miscible as far as I know. I think methanol must be used as solvent, as NaBH4 is not soluble in toluene.
was that directed at my question ?
So SWIM couldn't do it all one pot like the MM Al/hg reduction ?
whats the ratio of NaBh4 to Nitro to reduce it all to methylamine.
Could it be the nitro ---> methylamine de carried out in acidic conditions to generate methylamine.HCL ? (for storage)
Cheers