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Hydrogenolysis of Phenylalaninol.....

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java:
Mining the web and following up leads in related articles , I came upon a couple of studies dealing with the reduction of arene aliphatic alcohols, checked the archives and found no listings on the HIve and so I present them here now for discussion.......java

Chlorotrimethylsilane/SodiumIodide/Zinc as a Simple and Convenient Reducing System:One pot Deoxygenation of Alcohols and ethers

Tsuoshi Morita, Yoshiki Okamoto, Hiroshi sakurai
Synthesis 32, 1981





Note: with this method both primary and secondary alcohols are reduced to hydrocarbons

--- End quote ---


Synthetic Method and Reactions;47. AlCl/Pd-Catalyzed Reduction of Aryl Substituded Alcohols and Olefins by Hydrogen Transfer from Cyclohexene

George A. Olah ; G.K. Surya Prakash

Synthesis 397, 1978





Note: with this method it seems only benzylic alcohols are reduced, might be a good way to reduce Pseudo-ephedrine......


Edited.....by java

nightshade:
Fermenting phenylalanine in a bio brew like that producing L-Pac will will produce phenylalaniol, which can be extracted with a non polar solvent then reduced by electrochemical reaction to amphetamine is this correct?

java:
nightshade....  do you have some references for that?..........I myself not familiar with the way you've outlioned the procedure.....java

indole_amine:

nightshade:
Post 9775,Post 10417

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