Author Topic: Bromination variations  (Read 835 times)

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El_Zorro

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Bromination variations
« on: August 31, 2002, 10:44:00 PM »
I've been looking into the bromination of Vanillin, and I really liked the method of in-situ bromine generation.  Namely, uemura's method in

Post 297806

(uemura: "How to prepare hydroxyvanillin", Methods Discourse)
  But I was thinking of ways to possibly improve upon it.  First off, you have to add 35% H2O2, which is kind of volumetrically ineffiecient.  Could not solid calcium hypochlorite be used as the oxidizing agent?  But unless I am mistaken, the hypochlorite would react with the GAA, and produce Cl2 gas.  So would it work in plain old methanol?  In

Post 348265

(slothrop: "Bromination with NaBr and Oxone", Methods Discourse)
, they mention using oxone in methanol with KBr to brominate, but could calcium hypochlorite be used?  Thoughts?

Who is that masked man?