use torr *grrrr* nothing else.
30"Hg isent tat like 0 torr ???? ../rhodium/chemistry
/equipment/conversion.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry
/equipment/conversion.html)
Look at ../rhodium/chemistry
/equipment/nomograph.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry
/equipment/nomograph.html)
and wather boils at 0°C @ 10 torr so mopre than that is overkill
The melting point/decomposition temperature of Lysergic Acid is approx. 240 C.
In order to obtain Anhydrous Lysergic Acid, it needs to be heated at a fairly high temperature in a very good vacuum.
Lysergic Acid obtained from alkaline hydrolysis of ergot alkaloids crystalizes out with 1 mol. of H2O:
../rhodium/chemistry
/ergotinine2lysergic.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry
/ergotinine2lysergic.html)
"Lysergic acid (although rather sparingly soluble) can be recrystallized best from water. It crystallizes as very thin hexagonal leaflets which melt with decomposition at 238°C. The melting point varies somewhat with the rate of heating. Repeated recrystallization failed to raise the MP. It separates with approximately 1mol of water of crystallization. This water is held very tenaciously and can be removed completely only on drying at 140°C/2mmHg."
IMHO, If one is going to use Lysergic Acid in a reaction that utilizes moisture sensitive chemicals (i.e. the CDI LSD synthesis) it is better to use anhydrous Lysergic Acid then to have moisture form and "use up" the other chemicals such as N.N. Carbonyldiimidazole, etc.