oops. thats not what i meant. heres a more understandable form of my question. could fluoxetine undergo substitution with something like OH- as the attacking nucleophile at this site(*):
Ph
|
F3C-PhO-CH*-(CH2)2NHCH3
to yield:
Ph
|
Nu-CH(CH2)2NHCH3
(Nu is the incoming nucleophile)
As it is a benzylic carbon, i figure that site would readily undergo first order nucleophilic substitution (Sn1) with a stongly basic nucleophile. although i have a feeling that that only occurs with halogenated benzyls, at least on 2nd degree carbons. what do you think?
does anyone know or can think of any other pathways to this or a similar product from fluoxetine?
What do you do with a dead chemist?
...Barium