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(Assholium: "ãóòðîí? îêñèëèäèí!", Russian HyperLab)Removal of Acyl Protecting Groups Using Solid NaOH and a Phase Transfer CatalystSynlett 7,991-92,2003AbstractAcetyl-, benzoyl- and pivoyl-protected alcohols and phenols undergo smooth deacylation in a two-phase system of powdered NaOH and Bu4NHSO4 in THF or CH2Cl2.
SummaryWe have devised a new method for the removal of acetyl-, benzoyl- and some pivoyl-protecting groups from acyl protected alcohols utilizing a two-phase system with tetrabutylammonium hydrogen sulfate as phase transfer catalyst. Furthermore, based on our previous work,(15)this method does not affect alkyl silyl ethers but does deprotect aryl silyl ethers.
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Comments by Java Although this method was for phenols and alcohols , I wonder if it will work for amine acylated phenylalanine as a method of removal of the acyl group.