The Vespiary

The Hive => Tryptamine Chemistry => Topic started by: Maighstir on July 22, 2000, 11:49:00 AM

Title: looking for Rf values of DET-salts
Post by: Maighstir on July 22, 2000, 11:49:00 AM

Does anyone have Rf values of diethyltryptamine freebase and salts? Spec: silica 60 F254.

thanks,

Maighstir.

Vae victis meretrix est et mors venit.

Title: Re: looking for Rf values of DET-salts
Post by: Acme on July 24, 2000, 07:36:00 AM

You might try to elute it with chloroform/EtOH/aq ammonia
40:8:1. 

Title: Re: looking for Rf values of DET-salts
Post by: Maighstir on July 24, 2000, 02:47:00 PM

That's all very nice but what I'm looking for are Rf values for DET.

Vae victis meretrix est et mors venit.

Title: Re: looking for Rf values of DET-salts
Post by: Lilienthal on July 25, 2000, 01:07:00 PM

Don't rely to much on Rf, they are different from experiment to experiment (e.g. because of different activities of your plates or humidity in eluents).
I suggest to use Van Urk = Ehrlich reagent for the detection of indoles (p-dimethylaminobenzaldehyde in methanol / HCl conc., heat with hot air after immersion into the reagent, tryptamines give violet to blue -> gray spots) and two eluents, one acidic (few drops acetic acid added) and one basic (few drops triethylamine added). The basic tryptamines will have (greatly) different Rf, the nonbasic impurities (e.g. the very apolar skatoles) will have nearly the same Rf.